Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Jaundice
ADR ID BADD_A02422
ADR Hierarchy
01      Blood and lymphatic system disorders
01.06      Haemolyses and related conditions
01.06.04      Haemolyses NEC
01.06.04.004      Jaundice
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.01      Cholestasis and jaundice
09.01.01.004      Jaundice
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.03      Dermal and epidermal conditions NEC
23.03.03.030      Jaundice
Description A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction. [MeSH]
MedDRA Code 10023126
MeSH ID D007565; D007565; D007565
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Icterus | Jaundice | Jaundice (excl neonatal) | Jaundice NOS | Jaundice, unspecified, not of newborn | Subicteric | Jaundice, Hemolytic | Hemolytic Jaundice | Hemolytic Jaundices | Jaundices, Hemolytic
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Alanine aminotransferase 1P24298Not Available
Alkaline phosphatase, tissue-nonspecific isozymeP05186T09538
Glutathione hydrolase 7Q9UJ14T25122
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00410Celecoxib0.001378%
BADD_D00417Cetirizine0.000199%
BADD_D00429Chlorambucil--
BADD_D00432Chlordiazepoxide--
BADD_D00433Chlordiazepoxide hydrochloride--
BADD_D00442Chlorothiazide--
BADD_D00443Chlorothiazide sodium--
BADD_D00445Chlorpromazine0.002670%
BADD_D00446Chlorpromazine hydrochloride--
BADD_D00448Chlorthalidone--
BADD_D00453Cholic acid--
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00466Cilostazol--
BADD_D00467Cimetidine0.008597%
BADD_D00471Ciprofloxacin--
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00474Cisplatin--
BADD_D00475Citalopram0.000333%
BADD_D00476Citalopram hydrobromide--
BADD_D00480Clarithromycin0.002468%
BADD_D00483Clindamycin--
BADD_D00485Clindamycin palmitate hydrochloride--
BADD_D00486Clindamycin palmitate hydrochloride (pediatric)--
BADD_D00487Clindamycin phosphate--
BADD_D00495Clofarabine--
BADD_D00496Clofazimine--
BADD_D00497Clomiphene--
BADD_D00499Clomipramine--
BADD_D00504Clopidogrel--
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